Protective Effects of Methotrexate against Proatherosclerotic Cytokines: A Review of the Evidence

• Autors principals: Arduino A. Mangoni (Autor), Angelo Zinellu (Autor), Salvatore Sotgia (Autor), Ciriaco Carru (Autor), Matteo Piga (Autor), Gian Luca Erre (Autor)
• Format: Llibre
• Publicat: Hindawi Limited, 2017-01-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

There is good epidemiological evidence that patients with autoimmune rheumatic disease states, particularly rheumatoid arthritis, have an increased risk of cardiovascular morbidity and mortality when compared to the general population. The presence of a chronic systemic proinflammatory state in this...