Targeting cancer homing into the lymph node with a novel anti-CCR7 therapeutic antibody: the paradigm of CLL
Lymph node (LN) is a key tissue in the pathophysiology of mature blood cancers, especially for chronic lymphocytic leukemia (CLL). Within the multiple de-regulated pathways affecting CLL homeostasis, the CC-chemokine receptor 7 (CCR7) grants homing of CLL cells into the LN where protective environme...
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Main Authors: | Carlos Cuesta-Mateos (Author), Raquel Juárez-Sánchez (Author), Tamara Mateu-Albero (Author), Javier Loscertales (Author), Wim Mol (Author), Fernando Terrón (Author), Cecilia Muñoz-Calleja (Author) |
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Format: | Book |
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Taylor & Francis Group,
2021-01-01T00:00:00Z.
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