Development of a Parenteral Formulation of NTS-Polyplex Nanoparticles for Clinical Purpose

• Main Authors: María E. Aranda-Barradas (Author), Maripaz Márquez (Author), Liliana Quintanar (Author), Jaime Santoyo-Salazar (Author), Armando J. Espadas-Álvarez (Author), Daniel Martínez-Fong (Author), Elizabeth García-García (Author)
• Format: Book
• Published: MDPI AG, 2018-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Neurotensin (NTS)-polyplex is a nanoparticle system for targeted gene delivery that holds great promise for treatment of Parkinson's disease and various types of cancer. However, the high instability in aqueous suspension of NTS-polyplex nanoparticles is a major limitation for their widespread...