Modulation of Murine Macrophage TLR7/8-Mediated Cytokine Expression by Mesenchymal Stem Cell-Conditioned Medium

• Main Authors: Takahiro Asami (Author), Makoto Ishii (Author), Hideki Fujii (Author), Ho Namkoong (Author), Sadatomo Tasaka (Author), Kenichi Matsushita (Author), Ken Ishii (Author), Kazuma Yagi (Author), Hiroshi Fujiwara (Author), Yohei Funatsu (Author), Naoki Hasegawa (Author), Tomoko Betsuyaku (Author)
• Format: Book
• Published: Hindawi Limited, 2013-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Increasing evidence suggests that mesenchymal stem cells (MSCs) play anti-inflammatory roles during innate immune responses. However, little is known about the effect of MSCs or their secretions on the ligand response of Toll-like receptor (TLR) 7 and TLR8, receptors that recognize viral single-stra...