Adipocyte lipid synthesis coupled to neuronal control of thermogenic programming

• Main Authors: Adilson Guilherme (Author), David J. Pedersen (Author), Elizabeth Henchey (Author), Felipe S. Henriques (Author), Laura V. Danai (Author), Yuefei Shen (Author), Batuhan Yenilmez (Author), DaeYoung Jung (Author), Jason K. Kim (Author), Irfan J. Lodhi (Author), Clay F. Semenkovich (Author), Michael P. Czech (Author)
• Format: Book
• Published: Elsevier, 2017-08-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background: The de novo biosynthesis of fatty acids (DNL) through fatty acid synthase (FASN) in adipocytes is exquisitely regulated by nutrients, hormones, fasting, and obesity in mice and humans. However, the functions of DNL in adipocyte biology and in the regulation of systemic glucose homeostasi...