Enhancement of the Tumor Suppression Effect of High-dose Radiation by Low-dose Pre-radiation Through Inhibition of DNA Damage Repair and Increased Pyroptosis

• Main Authors: Xinfeng Wei (Author), Junxuan Yi (Author), Citong Zhang (Author), Mingwei Wang (Author), Rui Wang (Author), Weiqiang Xu (Author), Mingqi Zhao (Author), Mengdie Zhao (Author), Teng Yang (Author), Wei Wei (Author), Shunzi Jin (Author), Hui Gao (Author)
• Format: Book
• Published: SAGE Publishing, 2024-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Radiation therapy has been a critical and effective treatment for cancer. However, not all cells are destroyed by radiation due to the presence of tumor cell radioresistance. In the current study, we investigated the effect of low-dose radiation (LDR) on the tumor suppressive effect of high-dose rad...