Empagliflozin induces apoptotic-signaling pathway in embryonic vasculature: In vivo and in silico approaches via chick's yolk sac membrane model

• প্রধান লেখক: Saeedeh Mosallanejad (লেখক), Mehdi Mahmoodi (লেখক), Hadi Tavakkoli (লেখক), Ahmad Khosravi (লেখক), Ehsan Salarkia (লেখক), Alireza Keyhani (লেখক), Shahriar Dabiri (লেখক), Mohammad Hossein Gozashti (লেখক), Abbas Pardakhty (লেখক), Hadi Khodabandehloo (লেখক), Hossein Pourghadamyari (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Frontiers Media S.A., 2022-09-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

The present investigation was conducted to evaluate the vascular-toxicity of empagliflozin (EMP) in embryonic vasculature. Firstly, the vascular-toxicity of the drug as well as its interaction with apoptotic regulator proteins was predicted via in silico approach. In the next step, the apoptotic-sig...