Boosting synergism of chemo- and immuno-therapies via switching paclitaxel-induced apoptosis to mevalonate metabolism-triggered ferroptosis by bisphosphonate coordination lipid nanogranules

• Main Authors: Ge Song (Author), Minghui Li (Author), Shumin Fan (Author), Mengmeng Qin (Author), Bin Shao (Author), Wenbing Dai (Author), Hua Zhang (Author), Xueqing Wang (Author), Bing He (Author), Qiang Zhang (Author)
• Format: Book
• Published: Elsevier, 2024-02-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Conventional chemotherapy based on cytotoxic drugs is facing tough challenges recently following the advances of monoclonal antibodies and molecularly targeted drugs. It is critical to inspire new potential to remodel the value of this classical therapeutic strategy. Here, we fabricate bisphosphonat...