Reverse Remodeling in Human Heart Failure after Cardiac Resynchronization Therapy Is Associated With Reduced RHO-Kinase Activation

• मुख्य लेखकों: Maria Paz Ocaranza (लेखक), Jorge E. Jalil (लेखक), Rodrigo Altamirano (लेखक), Ana de León (लेखक), Jackeline Moya (लेखक), Alejandra Lonis (लेखक), Luigi Gabrielli (लेखक), Paul Mac Nab (लेखक), Samuel Córdova (लेखक), Alejandro Paredes (लेखक), Ismael Vergara (लेखक), Alex Bittner (लेखक), Karime Sabat (लेखक), Karla Pastorini (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Frontiers Media S.A., 2021-04-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Background: Reverse remodeling is a clinically relevant endpoint in heart failure with reduced ejection fraction (HFrEF). Rho-kinase (ROCK) signaling cascade activation correlates with cardiac remodeling and left ventricular (LV) systolic dysfunction in HFrEF patients. Cardiac resynchronization ther...