Reverse Remodeling in Human Heart Failure after Cardiac Resynchronization Therapy Is Associated With Reduced RHO-Kinase Activation

• Автори: Maria Paz Ocaranza (Автор), Jorge E. Jalil (Автор), Rodrigo Altamirano (Автор), Ana de León (Автор), Jackeline Moya (Автор), Alejandra Lonis (Автор), Luigi Gabrielli (Автор), Paul Mac Nab (Автор), Samuel Córdova (Автор), Alejandro Paredes (Автор), Ismael Vergara (Автор), Alex Bittner (Автор), Karime Sabat (Автор), Karla Pastorini (Автор)
• Формат: Книга
• Опубліковано: Frontiers Media S.A., 2021-04-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Background: Reverse remodeling is a clinically relevant endpoint in heart failure with reduced ejection fraction (HFrEF). Rho-kinase (ROCK) signaling cascade activation correlates with cardiac remodeling and left ventricular (LV) systolic dysfunction in HFrEF patients. Cardiac resynchronization ther...