DNA Methylation of TLR4, VEGFA, and DEFA5 Is Associated With Necrotizing Enterocolitis in Preterm Infants

• Główni autorzy: Daphne H. Klerk (Autor), Torsten Plösch (Autor), Rikst Nynke Verkaik-Schakel (Autor), Jan B. F. Hulscher (Autor), Elisabeth M. W. Kooi (Autor), Arend F. Bos (Autor)
• Format: Książka
• Wydane: Frontiers Media S.A., 2021-03-01T00:00:00Z.
• Hasła przedmiotowe: article
• Dostęp online: Connect to this object online.

Background: Epigenetic changes, such as DNA methylation, may contribute to an increased susceptibility for developing necrotizing enterocolitis (NEC) in preterm infants. We assessed DNA methylation in five NEC-associated genes, selected from literature: EPO, VEGFA, ENOS, DEFA5, and TLR4 in infants w...