GRK2 mediated degradation of SAV1 initiates hyperplasia of fibroblast-like synoviocytes in rheumatoid arthritis

• मुख्य लेखकों: Paipai Guo (लेखक), Ji Jiang (लेखक), Rui Chu (लेखक), Feng He (लेखक), Mingli Ge (लेखक), Ruhong Fang (लेखक), Qiuyun Guan (लेखक), Huijuan Cheng (लेखक), Chunru Jiang (लेखक), Tiantian Su (लेखक), Zhenduo Zhu (लेखक), Hao Liu (लेखक), Wei Wei (लेखक), Shihao Zhang (लेखक), Qingtong Wang (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: Elsevier, 2024-03-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Hyperplasia and migration of fibroblast-like synoviocytes (FLSs) are the key drivers in the pathogenesis of rheumatoid arthritis (RA) and joint destruction. Abundant Yes-associated protein (YAP), which is a powerful transcription co-activator for proliferative genes, was observed in the nucleus of i...