Site-Specific Impact of a Regional Hydrodynamic Injection: Computed Tomography Study during Hydrodynamic Injection Targeting the Swine Liver

• Main Authors: Takeshi Yokoo (Author), Tsutomu Kanefuji (Author), Takeshi Suda (Author), Kenya Kamimura (Author), Dexi Liu (Author), Shuji Terai (Author)
• Format: Book
• Published: MDPI AG, 2015-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A hemodynamic study of hydrodynamic gene delivery (HGD) from the tail vein in rodents has inspired a mechanism and an approach to further improve the efficacy of this procedure. However, there is no report on the hemodynamics of a regional HGD, which is an inevitable approach in large animals. Here,...