miRNome profiling of LSC-enriched CD34+CD38−CD26+ fraction in Ph+ CML-CP samples from Argentinean patients: a potential new pharmacogenomic tool

• Main Authors: María Sol Ruiz (Author), María Belén Sánchez (Author), Simone Bonecker (Author), Carolina Furtado (Author), Daniel Koile (Author), Patricio Yankilevich (Author), Santiago Cranco (Author), María del Rosario Custidiano (Author), Josefina Freitas (Author), Beatriz Moiraghi (Author), Mariel Ana Pérez (Author), Carolina Pavlovsky (Author), Ana Inés Varela (Author), Verónica Ventriglia (Author), Julio César Sánchez Ávalos (Author), Irene Larripa (Author), Ilana Zalcberg (Author), José Mordoh (Author), Peter Valent (Author), Michele Bianchini (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Chronic myeloid leukemia (CML) is a myeloid stem cell neoplasm characterized by an expansion of myeloid progenitor cells and the presence of BCR-ABL1 oncoprotein. Since the introduction of specific BCR-ABL1 tyrosine kinase inhibitors (TKI), overall survival has improved significantly. However, under...