EGCG synergizes the therapeutic effect of cisplatin and oxaliplatin through autophagic pathway in human colorectal cancer cells

• Main Authors: Fen Hu (Author), Fei Wei (Author), Yulei Wang (Author), Bibo Wu (Author), Yuan Fang (Author), Bin Xiong (Author)
• Format: Book
• Published: Elsevier, 2015-05-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Application of the platinum-based chemotherapy for colorectal cancer is restricted due to its severe cytotoxic effects. In this study we used synergistic strategies by combining (−)-Epigallocatechin gallate (EGCG) with cisplatin or oxaliplatin to minimize the ill effects of platinum-based therapy. M...