Santalol Isomers Inhibit Transthyretin Amyloidogenesis and Associated Pathologies in Caenorhabditis elegans
Transthyretin (TTR) is a homotetrameric protein found in human serum and is implicated in fatal inherited amyloidoses. Destabilization of native TTR confirmation resulting from mutation, environmental changes, and aging causes polymerization and amyloid fibril formation. Although several small molec...
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Main Authors: | , , , , , , , |
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Format: | Book |
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Frontiers Media S.A.,
2022-06-01T00:00:00Z.
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A1234.567 |
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