Triptolide in the treatment of systemic lupus erythematosus - regulatory effects on miR-146a in B cell TLR7 signaling pathway in mice

• Asıl Yazarlar: Yi Zhang (Yazar), FengQi Zhang (Yazar), YiNi Gao (Yazar), MeiJiao Wang (Yazar), Yan Gao (Yazar), HaiChang Li (Yazar), Jing Sun (Yazar), ChengPing Wen (Yazar), ZhiJun Xie (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Frontiers Media S.A., 2022-09-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Objective: To clarify the mechanism of triptolide (TP) in alleviating the conditions underlying SLE.Methods: Eight-week-old MRL/lpr mice were randomly divided into a model group (n = 5), low-dose TP (TP-L) group (n = 5), and high-dose TP (TP-H) group (n = 5). Mice in these groups were gavaged with n...