Inactivation of Zeb1 in GRHL2-deficient mouse embryos rescues mid-gestation viability and secondary palate closure

• প্রধান লেখক: Marina R. Carpinelli (লেখক), Michael E. de Vries (লেখক), Alana Auden (লেখক), Tariq Butt (লেখক), Zihao Deng (লেখক), Darren D. Partridge (লেখক), Lee B. Miles (লেখক), Smitha R. Georgy (লেখক), Jody J. Haigh (লেখক), Charbel Darido (লেখক), Simone Brabletz (লেখক), Thomas Brabletz (লেখক), Marc P. Stemmler (লেখক), Sebastian Dworkin (লেখক), Stephen M. Jane (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: The Company of Biologists, 2020-03-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Cleft lip and palate are common birth defects resulting from failure of the facial processes to fuse during development. The mammalian grainyhead-like (Grhl1-3) genes play key roles in a number of tissue fusion processes including neurulation, epidermal wound healing and eyelid fusion. One family me...