Transport of six tyrosine kinase inhibitors: active or passive?

• প্রধান লেখক: Richard J. Honeywell (লেখক), Sarina Hitzerd (লেখক), Ietje Kathmann (লেখক), Godefridus J. Peters (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: International Association of Physical Chemists (IAPC), 2016-03-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Transport of erlotinib, gefitinib, sorafenib, sunitinib, dasatinib and crizotinib can be active or passive, which was studied by measuring uptake  at low (4 °C; passive) and normal temperature (37 °C; active and passive) and by the use of specific organic cation transporter (OCT) inhibitors. Intrace...