PIAS3 suppresses damage in an Alzheimer's disease cell model by inducing the STAT3-associated STAT3/Nestin/Nrf2/HO-1 pathway

• Main Authors: Chen Li (Author), Ruili Wang (Author), Youyou Zhang (Author), Chunting Hu (Author), Qiaoya Ma (Author)
• Format: Bog
• Udgivet: BMC, 2021-11-01T00:00:00Z.
• Fag: article
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Abstract Background Alzheimer's disease (AD), the most common form of dementia, is caused by the degeneration of the central nervous system (CNS). A previous study reported that signal transducer and activator of transcription 3 (STAT3) is activated during AD development; nonetheless, the relat...