Discovery of natural anthraquinones as potent inhibitors against pancreatic lipase: structure-activity relationships and inhibitory mechanism

• Main Authors: Zi-Qiang Chen (Author), Wen-Yao He (Author), Si-Yuan Yang (Author), Hong-Hong Ma (Author), Jing Zhou (Author), Hao Li (Author), Ya-Di Zhu (Author), Xing-Kai Qian (Author), Li-Wei Zou (Author)
• Format: Book
• Published: Taylor & Francis Group, 2024-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Obesity is acknowledged as a significant risk factor for various metabolic diseases, and the inhibition of human pancreatic lipase (hPL) can impede lipid digestion and absorption, thereby offering potential benefits for obesity treatment. Anthraquinones is a kind of natural and synthetic compounds w...