CD3 aptamers promote expansion and persistence of tumor-reactive T cells for adoptive T cell therapy in cancer
The CD3/T cell receptor (TCR) complex is responsible for antigen-specific pathogen recognition by T cells, and initiates the signaling cascade necessary for activation of effector functions. CD3 agonistic antibodies are commonly used to expand T lymphocytes in a wide range of clinical applications,...
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2024-06-01T00:00:00Z.
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