Strong and Selective Inhibitory Effects of the Biflavonoid Selamariscina A against CYP2C8 and CYP2C9 Enzyme Activities in Human Liver Microsomes

• Main Authors: So-Young Park (Author), Phi-Hung Nguyen (Author), Gahyun Kim (Author), Su-Nyeong Jang (Author), Ga-Hyun Lee (Author), Nguyen Minh Phuc (Author), Zhexue Wu (Author), Kwang-Hyeon Liu (Author)
• Format: Book
• Published: MDPI AG, 2020-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Like flavonoids, biflavonoids, dimeric flavonoids, and polyphenolic plant secondary metabolites have antioxidant, antibacterial, antiviral, anti-inflammatory, and anti-cancer properties. However, there is limited data on their effects on cytochrome P450 (P450) and uridine 5'-diphosphoglucuronos...