Discovery of novel 1,3-diaryltriazene sulfonamides as carbonic anhydrase I, II, VII, and IX inhibitors

• Main Authors: Suleyman Akocak (Author), Nabih Lolak (Author), Silvia Bua (Author), Claudiu T. Supuran (Author)
• פורמט: ספר
• יצא לאור: Taylor & Francis Group, 2018-01-01T00:00:00Z.
• נושאים: article
• גישה מקוונת: Connect to this object online.

A series of new 1,3-diaryltriazene sulfonamides was synthesised by reaction of diazonium salt of metanilamide (3-aminobenzene sulfonamide) with substituted aromatic amines. The obtained new compounds were assayed as inhibitors of four physiologically and pharmacologically relevant human (h) isoforms...