Mechanochemical Synthesis of A Novel Eutectic of the Antimicrobial Nitazoxanide with Improved Dissolution Performance

• 主要な著者: Octavio E. Fandiño (著者), Flavia P Bruno (著者), Gustavo A. Monti (著者), Norma R. Sperandeo (著者)
• フォーマット: 図書
• 出版事項: Tabriz University of Medical Sciences, 2021-12-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Background: Nitazoxanide (NTZ) is a broad spectrum antimicrobial agent with poor aqueous solubility and low bioavailability. Thus, the generation of new solid forms of NTZ is relevant to improve its unfavorable properties. The present study deals with the application of mechanochemistry for the prep...