Transcriptional Factor Yin Yang 1 Promotes the Stemness of Breast Cancer Cells by Suppressing miR-873-5p Transcriptional Activity

• Main Authors: Qianqian Guo (Author), Ting Wang (Author), Yue Yang (Author), Lanlan Gao (Author), Qiong Zhao (Author), Wenzhou Zhang (Author), Tao Xi (Author), Lufeng Zheng (Author)
• Format: Book
• Published: Elsevier, 2020-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Transcription factor Yin Yang 1 (YY1) is upregulated in multiple tumors and plays essential roles in tumor proliferation and metastasis. However, the function of YY1 in breast cancer stemness remains unclear. Herein, we found that YY1 expression was negatively correlated with the overall survival an...