Noscapine hydrochloride (benzyl-isoquinoline alkaloid) effectively prevents protein denaturation through reduction of IL-6, NF-kB, COX-2, Prostaglandin-E2 in rheumatic rats

• Main Authors: Shanila Akhter (Author), Hafiz Muhammad Irfan (Author), Alamgeer (Author), Aman Ullah (Author), Shah Jahan (Author), Muhammad Roman (Author), Muhammad Bilal Latif (Author), Zaid Mustafa (Author), Farooq M. Almutairi (Author), Yusuf S. Althobaiti (Author)
• Format: Book
• Published: Elsevier, 2022-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Noscapine hydrochloride (benzyl-isoquinoline antitussive alkaloid) is an opium derivative and generally used as a cough suppressant. Numerous studies on noscapine hydrochloride have reported that it has potent anti-inflammatory activity. However, the mechanisms by which it exerts an anti-inflammator...