Hepatic COX1 loss leads to impaired autophagic flux and exacerbates nonalcoholic steatohepatitis
The mechanisms underlying autophagic defects in nonalcoholic steatohepatitis (NASH) remain largely unknown. We aimed to elucidate the roles of hepatic cyclooxygenase 1 (COX1) in autophagy and the pathogenesis of diet-induced steatohepatitis in mice. Human nonalcoholic fatty liver disease (NAFLD) liv...
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| Main Authors: | , , , , , , , , , , , , , , |
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| Format: | Book |
| Published: |
Elsevier,
2023-06-01T00:00:00Z.
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| Subjects: | |
| Online Access: | Connect to this object online. |
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