Mammalian target of rapamycin inhibition impacts energy homeostasis and induces sex‐specific body weight loss in humans
Abstract Background Previous data from a 2‐year randomized controlled trial (CRAD001ADE12) indicated that mammalian target of rapamycin (mTOR) inhibition by everolimus slowed cyst growth in patients with autosomal‐dominant polycystic kidney disease (ADPKD). During the trial, we noted body weight los...
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Main Authors: | Marwan Mannaa (Author), Pia Pfennigwerth (Author), Jens Fielitz (Author), Maik Gollasch (Author), Michael Boschmann (Author) |
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Format: | Book |
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Wiley,
2023-12-01T00:00:00Z.
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