Immunocytochemical Characterization of Alzheimer's Disease Hallmarks in APP/PS1 Transgenic Mice Treated with a New Anti-Amyloid-β Vaccine

• المؤلفون الرئيسيون: Ivan Carrera (مؤلف), Ignacio Etcheverria (مؤلف), Yi Li (مؤلف), Lucia Fernandez-Novoa (مؤلف), Valter Lombardi (مؤلف), Carmen Vigo (مؤلف), Hector H. Palacios (مؤلف), Valery V. Benberin (مؤلف), Ramon Cacabelos (مؤلف), Gjumrakch Aliev (مؤلف)
• التنسيق: كتاب
• منشور في: University Library System, University of Pittsburgh, 2014-03-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Introduction: APP/PS1 double-transgenic mouse models of Alzheimer's disease (AD), which overexpress mutated forms of the gene for the human amyloid precursor protein (APP) and presenilin 1 (PS1), have provided robust neuropathological hallmarks of an AD-like pattern at early ages. This study ai...