PLD1 knockdown reduces metastasis and inflammation of fibroblast-like synoviocytes in rheumatoid arthritis by modulating NF-κB and Wnt/β-catenin pathways

• Main Authors: Zhengyu Zhang (Author), Xi Chen (Author), Bo Gao (Author), Guomin Sun (Author), Yan Wang (Author), Junke Wang (Author), Ting Zhang (Author), Hao Qian (Author), Yu Zhang (Author), Jun Huang (Author), Rurong Sun (Author), Jiabiao Wu (Author), Lei Zhou (Author)
• Format: Book
• Published: Taylor & Francis Group, 2021-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Considered as an autoimmune disease, rheumatoid arthritis (RA) is an chronic inflammatory disorder that causes inflammation of the joints. This study is performed with the aim to clarify the expression of phospholipase D1 (PLD1) in RA and its specific regulation role of RA as well as the underlying...