Advances in RIPK1 kinase inhibitors

• Main Authors: Lu Chen (Author), Xiaoqin Zhang (Author), Yaqing Ou (Author), Maoyu Liu (Author), Dongke Yu (Author), Zhiheng Song (Author), Lihong Niu (Author), Lijuan Zhang (Author), Jianyou Shi (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Programmed necrosis is a new modulated cell death mode with necrotizing morphological characteristics. Receptor interacting protein 1 (RIPK1) is a critical mediator of the programmed necrosis pathway that is involved in stroke, myocardial infarction, fatal systemic inflammatory response syndrome, Al...