Investigation of Molecular Weight, Polymer Concentration and Process Parameters Factors on the Sustained Release of the Anti-Multiple-Sclerosis Agent Teriflunomide from Poly(<i>ε</i>-caprolactone) Electrospun Nanofibrous Matrices

Investigation of Molecular Weight, Polymer Concentration and Process Parameters Factors on the Sustained Release of the Anti-Multiple-Sclerosis Agent Teriflunomide from Poly(<i>ε</i>-caprolactone) Electrospun Nanofibrous Matrices

In the current work, a series of PCL polyesters with different molecular weights was synthesized and used for the fabrication of nanofibrous patches via electrospinning, as sustained release matrices for leflunomide's active metabolite, teriflunomide (TFL). The electrospinning conditions for ea...

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Main Authors: Nikolaos D. Bikiaris (Author), Ioanna Koumentakou (Author), Georgia Michailidou (Author), Margaritis Kostoglou (Author), Marilena Vlachou (Author), Panagiotis Barmpalexis (Author), Evangelos Karavas (Author), George Z. Papageorgiou (Author)
Format: Book
Published: MDPI AG, 2022-08-01T00:00:00Z.
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