NADPH Oxidase 5 Induces Changes in the Unfolded Protein Response in Human Aortic Endothelial Cells and in Endothelial-Specific <i>Knock-in</i> Mice

• Glavni autori: Adriana Cortés (Autor), Álvaro Pejenaute (Autor), Javier Marqués (Autor), Íñigo Izal (Autor), Silvia Cenoz (Autor), Eduardo Ansorena (Autor), Juan José Martínez-Irujo (Autor), Carlos de Miguel (Autor), Guillermo Zalba (Autor)
• Format: Knjiga
• Izdano: MDPI AG, 2021-01-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Oxidative stress constitutes a key molecular mechanism in the development of cardiovascular diseases. A potential relationship between reactive oxygen species (ROS) driven by the NADPH oxidase family (NOX) and the unfolded protein response (UPR) has been postulated. Nevertheless, there is a lack of...