Biotin-Decorated PAMAM G4.5 Dendrimer Nanoparticles to Enhance the Delivery, Anti-Proliferative, and Apoptotic Effects of Chemotherapeutic Drug in Cancer Cells

• Hlavní autoři: Endiries Yibru Hanurry (Autor), Tefera Worku Mekonnen (Autor), Abegaz Tizazu Andrgie (Autor), Haile Fentahun Darge (Autor), Yihenew Simegniew Birhan (Autor), Wei-Hsin Hsu (Autor), Hsiao-Ying Chou (Autor), Chih-Chia Cheng (Autor), Juin-Yih Lai (Autor), Hsieh-Chih Tsai (Autor)
• Médium: Kniha
• Vydáno: MDPI AG, 2020-05-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

Biotin receptors are overexpressed by various types of solid cancer cells and play a significant role in tumor metabolism, growth, and metastasis. Thus, targeting the biotin receptors on tumor cells may enhance the efficiency and reduce the side-effects of chemotherapy. The aim of this study was to...