Decoding the anti-hypertensive mechanism of α-mangostin based on network pharmacology, molecular docking and experimental validation

• Main Authors: Qi-Qi Xue (Author), Chu-Hao Liu (Author), Yan Li (Author)
• Format: Bog
• Udgivet: BMC, 2024-11-01T00:00:00Z.
• Fag: article
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Abstract Background Hypertension is a leading risk factor for disability and deaths worldwide. Evidence indicates that alpha-mangostin(α-MG) can reduce blood pressure and improve target organ damage. Nonetheless, its pharmacological targets and potential mechanisms of action remain inadequately eluc...