Selective Nitro Reduction of Ester Substituted Nitroarenes by NaBH4-FeCl2

• Main Authors: Zi-Hong Zhou (Author), Yong-Bo Xu (Author), Shu-Ming Wu (Author), Wei-Jian Ling (Author), Lei Zhang (Author), Zhong-Qing Wang (Author)
• Format: Book
• Published: Georg Thieme Verlag KG, 2022-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract This work aimed to explore a novel protocol for selective reduction of the nitro group on the aromatic ring while remaining the ester group unaffected. In this study, NaBH4-FeCl2 was disclosed as a key reductant in the process. NaBH4-FeCl2-mediated reduction showed high chemoselectivity, ga...