Establishing a high throughput drug screening system for cerebral ischemia using zebrafish larvae

• Main Authors: Mami Matsumoto (Author), Moeri Miyamoto (Author), Masahito Sawahata (Author), Yasuhiko Izumi (Author), Yuki Takada-Takatori (Author), Toshiaki Kume (Author)
• Format: Book
• Published: Elsevier, 2021-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

We previously generated an ischemic stroke in a zebrafish model using N2 gas perfusion; however, this model was an unsuitable drug screening system due to low throughput. In this study, we examined a zebrafish ischemic stroke model using an oxygen absorber to assess drug effects. Hypoxic exposure mo...