Contribution of Elevated Glucose and Oxidized LDL to Macrophage Inflammation: A Role for PRAS40/Akt-Dependent Shedding of Soluble CD14

• Autori principali: Lucía Sanjurjo (Autore), Esmeralda Castelblanco (Autore), Josep Julve (Autore), Nuria Villalmanzo (Autore), Érica Téllez (Autore), Anna Ramirez-Morros (Autore), Núria Alonso (Autore), Dídac Mauricio (Autore), Maria-Rosa Sarrias (Autore)
• Natura: Libro
• Pubblicazione: MDPI AG, 2023-05-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

Atherosclerosis, a process in which macrophages play a key role, is accelerated in diabetes. Elevated concentrations of serum-oxidized low-density lipoproteins (oxLDL) represent a common feature of both conditions. The main goal of this study was to determine the contribution of oxLDL to the inflamm...