Long-term stability of gentamicin sulfate-ethylenediaminetetraacetic acid disodium salt (EDTA-Na2) solution for catheter locks

• Main Authors: Anne-Sophie Fiolet (Author), Elise Jandot (Author), Pauline Doucey (Author), Coralie Crétet (Author), Célia Brunel (Author), Christine Pivot (Author), Jean-Marc Ghigo (Author), Christophe Beloin (Author), David Lebeaux (Author), Fabrice Pirot (Author)
• Format: Book
• Published: Elsevier, 2018-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

A lock solution composed of gentamicin sulfate (5 mg/mL) and ethylenediaminetetraacetic acid disodium salt (EDTA-Na2, 30 mg/mL) could fully eradicate in vivo bacterial biofilms in totally implantable venous access ports (TIVAP). In this study, fabrication, conditioning and sterilization processes of...