Gellan Gum Promotes the Differentiation of Enterocytes from Human Induced Pluripotent Stem Cells

• Main Authors: Shimeng Qiu (Author), Tomoki Kabeya (Author), Isamu Ogawa (Author), Shiho Anno (Author), Hisato Hayashi (Author), Tatsuro Kanaki (Author), Tadahiro Hashita (Author), Takahiro Iwao (Author), Tamihide Matsunaga (Author)
• Format: Book
• Published: MDPI AG, 2020-10-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

The evaluation of drug pharmacokinetics in the small intestine is critical for developing orally administered drugs. Caucasian colon adenocarcinoma (Caco-2) cells are employed to evaluate drug absorption in preclinical trials of drug development. However, the pharmacokinetic characteristics of Caco-...