Mechanism of Human Urotensin II-Induced Contraction in Rat Aorta

• Asıl Yazarlar: Katsunari Tasaki (Yazar), Masatoshi Hori (Yazar), Hiroshi Ozaki (Yazar), Hideaki Karaki (Yazar), Ichiro Wakabayashi (Yazar)
• Materyal Türü: Kitap
• Baskı/Yayın Bilgisi: Elsevier, 2004-01-01T00:00:00Z.
• Konular: article
• Online Erişim: Connect to this object online.

Urotensin II induced sustained contraction with an EC50 value of 2.29 ± 0.12 nM in rat aorta. Urotensin II (100 nM) transiently increased cytosolic Ca2+ level ([Ca2+]i), followed by a small sustained phase superimposed with rhythmic oscillatory change. In the presence of verapamil and La3+, the [Ca2...