Mechanism of Human Urotensin II-Induced Contraction in Rat Aorta
Urotensin II induced sustained contraction with an EC50 value of 2.29 ± 0.12 nM in rat aorta. Urotensin II (100 nM) transiently increased cytosolic Ca2+ level ([Ca2+]i), followed by a small sustained phase superimposed with rhythmic oscillatory change. In the presence of verapamil and La3+, the [Ca2...
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Elsevier,
2004-01-01T00:00:00Z.
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A1234.567 |
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