Impact of CDK4/6 Inhibitors on Aromatase Inhibitor-Associated Musculoskeletal Syndrome (AIMSS) in the Adjuvant Setting

• Main Authors: Efthymia Skafida (Author), Angeliki Andrikopoulou (Author), Evangelos Terpos (Author), Christos Markellos (Author), Savvina Moustafa (Author), Dimitrios Pectasides (Author), Meletios-Athanasios Dimopoulos (Author), Flora Zagouri (Author), Dimitrios Vassilopoulos (Author)
• Format: Book
• Published: Hindawi-Wiley, 2023-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background. Third-generation aromatase inhibitors (AIs) are the mainstay of treatment in hormone receptor (HR)-positive breast cancer. Even though it is considered to be a well-tolerated therapy, AI-induced musculoskeletal symptoms are common and may be accused for treatment discontinuation. Recentl...