Pretargeted Imaging with Gallium-68-Improving the Binding Capability by Increasing the Number of Tetrazine Motifs

• Váldodahkkit: Dominik Summer (Dahkki), Sonja Mayr (Dahkki), Milos Petrik (Dahkki), Christine Rangger (Dahkki), Katia Schoeler (Dahkki), Lisa Vieider (Dahkki), Barbara Matuszczak (Dahkki), Clemens Decristoforo (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: MDPI AG, 2018-10-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

The inverse electron-demand Diels-Alder reaction between 1,2,4,5-tetrazine (Tz) and trans-cyclooct-2-ene (TCO) has gained increasing attraction among extensive studies on click chemistry due to its exceptionally fast reaction kinetics and high selectivity for in vivo pretargeting applications includ...