Topical Delivery of 3-O-ethyl l-ascorbic Acid from Complex Solvent Systems

• Autori principali: Fotis Iliopoulos (Autore), A. S. M. Monjur Al Hossain (Autore), Bruno C. Sil (Autore), David J. Moore (Autore), Robert A. Lucas (Autore), Majella E. Lane (Autore)
• Natura: Libro
• Pubblicazione: MDPI AG, 2020-04-01T00:00:00Z.
• Soggetti: article
• Accesso online: Connect to this object online.

3-O-ethyl l-ascorbic acid (EA), an ether derivative of Vitamin C, is widely used in skincare formulations. Previously, we reported the effects of neat solvents on EA percutaneous absorption and observed that 0.6-7.5% of the applied EA was delivered through the skin over 24 h. In this work, we design...