Journey of TRAIL from bench to bedside and its potential role in immuno-oncology

• Main Authors: George E. Naoum (Author), Donald J. Buchsbaum (Author), Fady Tawadros (Author), Ammad Farooqi (Author), Waleed O. Arafat (Author)
• Format: Book
• Published: Frontiers Media S.A., 2017-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Induction of apoptosis in cancer cells has increasingly been the focus of many therapeutic approaches in oncology field. Since its identification as a TNF family member, TRAIL (TNF-related apoptosis-inducing ligand) paved a new path in apoptosis inducing cancer therapies. Its selective ability to ac...