Journey of TRAIL from bench to bedside and its potential role in immuno-oncology

• Главные авторы: George E. Naoum (Автор), Donald J. Buchsbaum (Автор), Fady Tawadros (Автор), Ammad Farooqi (Автор), Waleed O. Arafat (Автор)
• Формат: ‌
• Опубликовано: Frontiers Media S.A., 2017-04-01T00:00:00Z.
• Предметы: article
• Online-ссылка: Connect to this object online.

Induction of apoptosis in cancer cells has increasingly been the focus of many therapeutic approaches in oncology field. Since its identification as a TNF family member, TRAIL (TNF-related apoptosis-inducing ligand) paved a new path in apoptosis inducing cancer therapies. Its selective ability to ac...