Journey of TRAIL from bench to bedside and its potential role in immuno-oncology

• Autores principales: George E. Naoum (Autor), Donald J. Buchsbaum (Autor), Fady Tawadros (Autor), Ammad Farooqi (Autor), Waleed O. Arafat (Autor)
• Formato: Libro
• Publicado: Frontiers Media S.A., 2017-04-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

Induction of apoptosis in cancer cells has increasingly been the focus of many therapeutic approaches in oncology field. Since its identification as a TNF family member, TRAIL (TNF-related apoptosis-inducing ligand) paved a new path in apoptosis inducing cancer therapies. Its selective ability to ac...