Whole-genome bisulfite sequencing in systemic sclerosis provides novel targets to understand disease pathogenesis

• मुख्य लेखकों: Tianyuan Lu (लेखक), Kathleen Oros Klein (लेखक), Inés Colmegna (लेखक), Maximilien Lora (लेखक), Celia M. T. Greenwood (लेखक), Marie Hudson (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: BMC, 2019-10-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Abstract Background Systemic sclerosis (SSc) is a rare autoimmune connective tissue disease whose pathogenesis remains incompletely understood. Increasing evidence suggests that both genetic susceptibilities and changes in DNA methylation influence pivotal biological pathways and thereby contribute...