Voluntary exercise influences metastatic organotropism in a murine colorectal cancer model

• Main Authors: Liza A. Wijler (Author), Danielle A.E. Raats (Author), Andre Verheem (Author), Anna M. denOtter (Author), Helene Rundqvist (Author), Miriam vanDijk (Author), Anne M. May (Author), Onno Kranenburg (Author)
• Format: Book
• Published: Wiley, 2022-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Physical activity is associated with a lower risk of colorectal cancer (CRC) and CRC‐specific mortality. However, evidence for a causal relationship between physical activity and disease progression is lacking. Here, we have used CRC organoids to create a novel mouse model for sp...