Pharmacometabolomics identifies candidate predictor metabolites of an L‐carnitine treatment mortality benefit in septic shock

Pharmacometabolomics identifies candidate predictor metabolites of an L‐carnitine treatment mortality benefit in septic shock

Abstract Sepsis‐induced metabolic dysfunction contributes to organ failure and death. L‐carnitine has shown promise for septic shock, but a recent phase II study of patients with vasopressor‐dependent septic shock demonstrated a non‐significant reduction in mortality. We undertook a pharmacometabolo...

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Main Authors: Michael A. Puskarich (Author), Theodore S. Jennaro (Author), Christopher E. Gillies (Author), Charles R. Evans (Author), Alla Karnovsky (Author), Cora E. McHugh (Author), Thomas L. Flott (Author), Alan E. Jones (Author), Kathleen A. Stringer (Author), for the RACE Investigators (Author)
Format: Book
Published: Wiley, 2021-11-01T00:00:00Z.
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3rd Floor Main Library

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